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Bisphosphonates are drugs that inhibit the normal biological mechanism for bone maintenance/repair, which can lead to an accumulation of micro-damage and bone fragility.

Bisphosphonates can also cause retention of calcified growth cartilage in skeletally immature animals, leading to developmental orthopaedic disease.

To compound these issues, bisphosphonates are potent analgesics and may disguise the signs of underlying serious orthopaedic injuries such as stress fractures in young animals.

Racing Australia advises that, for these reasons, bisphosphonates should never be used in young, skeletally immature, athletic horses.

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